A bilirubin in urine test measures the levels of bilirubin in your urine. Bilirubin is a yellowish substance made during the body's normal process of breaking down red blood cells. Bilirubin is found in bile, a fluid in your liver that helps you digest food. If your liver is healthy, it will remove most of the bilirubin from your body. If your liver is damaged, bilirubin can leak into the blood and urine. Bilirubin in urine may be a sign of liver disease.

Other names: urine test, urine analysis, UA, chemical urinalysis, direct bilirubin

Your health care provider may have ordered a bilirubin in urine test as part of your regular checkup, or if you have symptoms of liver disease. These symptoms include:

• Jaundice, a condition that causes your skin and eyes to turn yellow
• Dark-colored urine
• Abdominal pain
• Nausea and vomiting
• Fatigue

Because bilirubin in urine can indicate liver damage before other symptoms appear, your health care provider may order a bilirubin in urine test if you are at a higher risk for liver damage. Risk factors for liver disease include:

• Family history of liver disease
• Heavy drinking
• Exposure or possible exposure to hepatitis virus
• Obesity
• Diabetes
• Taking certain medicines that can cause liver damage

Your health care provider will need to collect a sample of your urine. During your office visit, you will receive a container to collect the urine and special instructions to make sure that the sample is sterile. These instructions are often called the "clean catch method." The clean catch method includes the following steps:

1. Wash your hands.
2. Clean your genital area with a cleansing pad given to you by your provider. Men should wipe the tip of their penis. Women should open their labia and clean from front to back.
3. Start to urinate into the toilet.
4. Move the collection container under your urine stream.
5. Collect at least an ounce or two of urine into the container, which should have markings to indicate the amounts.
6. Finish urinating into the toilet.
7. Return the sample container to your health care provider.

There is no known risk to having a urinalysis or a bilirubin in urine test.

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